Joe Burrow said it was a “dream come true” to be picked first by the Cincinnati Bengals in the 2020 NFL draft.
The quarterback, 23, was expected to be top pick in the remotely held draft after an award-winning college season.
Defensive end Chase Young was drafted second by the Washington Redskins with the Detroit Lions taking cornerback Jeff Okudah as third pick.
“To jump up to number one overall is crazy to me,” said Burrow.
At the start of last season, Alabama quarterback Tua Tagovailoa was expected to win the Heisman Trophy for the best college player but Burrow claimed the award after leading Louisiana State University to the national championship.
Tagovailoa, 22, suffered a dislocated hip in November but was still taken by the Miami Dolphins with the fifth pick, after former Ohio State pair Young and Okudah, both 21.
It is the third straight year that the Heisman Trophy winner is the top pick – after Kyler Murray (2019) and Baker Mayfield (2018) – and Burrow joins Cam Newton (2011) as the only quarterbacks since 1967 to win the Heisman and the national championship in the season before being the first overall pick.